intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...

endotrachial intubation can have serious deleterious hemodynamic changes. hypertension and tachycardia are especially dangerous in coronary artery disease, intracranial hypertension. magnesium sulfate is known for its vasodilating properties. several studies have reported favorable protective hemodynamic properties of magnesium when used as a premedicant in cardiac or elderly patients. our aim ...

OBJECTIVE To compare efficacy and safety of 50 μgm misoprostol vaginal with oral for labor induction. METHODS 110 women at term gestation, Bishop score ≤4, with various indications for labor induction were randomized and double blinded. After decoding 51 women had received misoprostol orally and 52 vaginally, four hourly (maximum six doses) or till woman went into active labor. RESULTS Stat...

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DNA double-strand breaks are particularly deleterious lesions that can lead to genomic instability and cell death. We investigated the SOS response to double-strand breaks in both Escherichia coli and Bacillus subtilis. In E. coli, double-strand breaks induced by ionizing radiation resulted in SOS induction in virtually every cell. E. coli strains incapable of SOS induction were sensitive to io...

This paper focuses on the turbine-generator shaft models of double-cage Induction Generator (IG) based wind farm and its influence on the sub-synchronous resonance phenomenon. For this purpose, six different shaft models as 6-mass, 4-mass, 3-mass I, 3-mass II, 2-mass and 1-mass models are considered for double-cage IG wind-turbine. By using the linear modal analysis method, the effects of the d...

introduction: the acrosome is a sac shaped organelle contaning lysosomal enzyme that is located on the anterior of sperm head. during the acrosome reaction its content is released in the vicinity of the egg. the acrosome reacted sperm then penetrates through the egg barriers. there are several methods for evaluating the acrosomal status; some of those are complex, expensive and/or non-accurate ...